The official website for the Lupin the 3rd Part 6 anime has announced that the anime will air for a half-year continuous run, with the second half premiering in January 2022.
The story of Lupin the 3rd Part 6 is described as:
Gentleman thief Lupin III is back and ready for his next caper— unless legendary sleuth, Sherlock Holmes, has anything to say about it. When Holmes’ longtime partner, Dr. Watson, is murdered, none other than Lupin tops the suspects list. With Holmes fast closing in, Lupin must prove his innocence and bring a shadowy organization called The Raven to heel if he wants to live to steal another day.
The anime premiered on October 6, 2021. Sentai Filmworks licensed the new series for home video and streaming in North America, Australia, New Zealand, Scandinavian countries, and all Nordic Countries, and HIDIVE is streaming the anime.